Ultraviolet radiation therapy refers to physical therapy technology that uses ultraviolet rays to irradiate the human body to prevent and treat skin diseases. It is one of the basic methods for clinical treatment of various chronic skin diseases such as vitiligo and psoriasis in dermatology. The clinical application of ultraviolet light therapy is constantly improving with the continuous update of ultraviolet light sources.
Before Christ, people used sunlight to treat many diseases. The use of carbon arc lamps to treat lupus vulgaris by Finsen in modern times is the earliest record of using artificial light sources to treat skin lesions. For this reason, Finsen won the 1903 Nobel Prize in Physiology and Medicine. In the 20th century, Goeckerman began to use high-pressure mercury lamps combined with topical coal tar to treat psoriasis, and achieved good results. This was the beginning of modern phototherapy. Later, in the 1970s, Parrish combined psoralen and UVA to treat vitiligo and psoriasis and achieved good clinical results, also known as PUVA ultraviolet light therapy. In 1988, the Philips company in the Netherlands developed a fluorescent tube that can emit narrow-band UVB (narrow-band UVB, NBUVB) 311nm. Because NBUVB has a significant effect on the treatment of sensitive diseases such as vitiligo and psoriasis, but the side effects are obvious. Less than PUVA therapy, so it is quickly popularized in clinical practice. NBUVB ultraviolet light therapy has therefore become the basic therapy for the treatment of many chronic skin diseases in various clinical treatment guidelines.
In 1997, xenon chloride lasers and bulbs began to be used in clinical dermatology. Because the 308 UVB emitted by them has a single wavelength, concentrated energy, and the wavelength is shorter than 311nm, the biological effect is stronger, and the treatment course can be shortened, so it is widely used in limitations. The treatment of vitiligo and psoriasis is usually called 308 excimer laser ultraviolet phototherapy and 308 excimer light ultraviolet phototherapy.
Beginning in 2001, as light emitting diodes (LEDs) began to be widely used in the lighting field, UV solid-state LED light sources also began to develop and produce. However, due to its low luminous efficiency, it cannot be used in clinical treatment for more than ten years. In recent years, as the market scale of the deep-ultraviolet field has attracted more and more attention from enterprises, ultraviolet (UV) LED-related technologies have advanced by leaps and bounds, and commercial applications of LED light sources such as UVA, UVB, and UVC in certain bands have been realized.
Working Principle
LED is a solid-state semiconductor device that can directly convert electrical energy into ultraviolet light. Each LED is composed of a PN junction, which has the characteristic of unidirectional conduction. When the forward voltage is applied to the light-emitting diode, the holes injected from the P area to the N area and the electrons injected from the N area to the P area recombine with the electrons in the N area and the holes in the P area respectively near the PN junction. Fluorescence that produces spontaneous emission. LEDs made of different materials emit light of different wavelengths. JF 308 LED UV light made of aluminum gallium nitride (AlGaN), a third-generation semiconductor material, can emit ultraviolet light with a peak wavelength of 308nm and other narrow UVB bands.
Features
Compared with xenon chloride excimer lamp, JF 308 LED light source has the following characteristics: ①Low voltage can be started, high safety, low electromagnetic radiation, 308 excimer lamp needs high frequency and high voltage to start operation, and the radiation is higher during operation, not suitable for home use; ②The light source is a semiconductor solid-state light source, with a lifespan of more than 5000 hours, and there is almost no attenuation of the intensity during use. As the use time increases, the intensity of the lamp tube will be attenuated to a greater extent; ③JF 308nm LED single light source is small in size and can be flexibly combined into different shapes, while the 308 excimer lamp does not have this characteristic. At the same time, the JF 308 LED light source also has significant advantages such as environmental protection and high portability at home.
Application
JF 308 LED is suitable for various skin lesions treated by 308nm ultraviolet rays.
Only from the perspective of manufacturing cost: In the current technology stage, the cost of manufacturing UVLED chips is relatively high. In particular, the price of the JF LED chip with a precise 308nm wavelength and high output power and stability is much higher than that of similar UV LEDs with a peak wavelength of ±3 to 5nm. Therefore, the prices of UVLED products with different standards vary greatly. As far as the actual manufacturing cost is concerned, it is preferable that the UV light therapy device with JF LED light source is higher than that of traditional excimer bulb products.
At the same time, the cost of the JF 308 LED light source is positively related to the number of chips. For chips of the same quality, the larger the area of the light source that needs to be composed, the higher the cost of the entire light source component.
It is foreseeable that as more and more chip manufacturers around the world join and continue to invest in UV LED, the rapid development of UV LED will bring better UV treatment cost-effectiveness to medical institutions and patients.
Precautions
1) The 308nm wavelength is shorter than the usual 311 UVB therapy. Therefore, in the treatment, the initial dose setting needs to be lower than the value of 311 ultraviolet light therapy. If it is a continuous 311nm UVB therapy that needs to be replaced with JF 308 LED therapy, the therapeutic dose should also be reduced by 20% about.
2) The difference between medical institution use and home use: At present, JF 308 LED ultraviolet light therapy device has three types of home use. ①The difference is that the requirements of home use standards are stricter. In terms of electromagnetic compatibility and safety, the requirements of home use standards are higher. For example, the medical standards for electromagnetic compatibility are: Electromagnetic emission must meet GB4824 Group 2 Class A, and there is no need to perform harmonic emission and flicker emission detection, while the domestic standard is: Electromagnetic emission must meet GB4824 Group 1 Class B (lower and safer Electromagnetic emission requirements), and to meet the detection requirements of harmonic emission and flicker emission.
②The intended home use phototherapy in the medical device registration certificate and manual will be marked with the words for the patient’s own use; the medical equipment will be marked with the words for the use of medical institutions.
Therefore, when performing ultraviolet light therapy treatment, especially at home, pay attention to choosing products that can be used in the home environment.
